Question

Expression of the int-l gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice

Answer 1

Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice. ... Transcriptional activation of the int-1 gene by proviral insertion mutations is thought to be a key step in mammary tumor induction by the mouse mammary tumor virus (MMTV).