Question

factors affecting the reactivity of carboxylic acid derivatives with nucleophilic reagent​

Answer 1

Answer:

This analysis also predicts the influence these substituent groups have on the reactivity of carboxylic acid derivatives toward nucleophiles (Z = O in the illustration). Inductive electron withdrawal by Y increases the electrophilic character of the carbonyl carbon, and increases its reactivity toward nucleophiles.

jai hind