Science, asked by manurawat12, 6 months ago

felder linkers – was tried I managed to finish the work all (through but yet)​

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Answered by Anonymous
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Answer:

Abstract

A PEG–haloperidol conjugate containing a non-biodegradable linker was synthesised. Incubation with rat plasma demonstrated excellent linker stability, and competition raand binding assays demonstrated retained binding to the D2-receptor. In silico studies predicted that the conjugate will not cross the blood–brain barrier (BBB), thus potentially restricting haloperidol action to one side of the BBB.

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