Find out about the mutant variety and triple mutant variety of coronavirus.
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The double mutant in India carried two mutations—E484Q and L452R—in the crucial spike protein part of the pathogen. Both the E484Q mutation (reported in both UK and South African variants) and L452R mutation (found in the California strain) have been associated with much greater binding and antibody escape capabilities.
In his thread, Scaria says that the new strain is characterised by the deletion of two amino acids (H146del and Y145del), as well as possessing E484K and D614G variants in spike protein. All this, according to him, helps in increased infectivity capabilities.
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