Find the concentration of procaine
hydrochloride required to make a solution isotonic with
blood plasma. The freezing point of 1% w/v solution of
procaine hydrochloride is -0.122°C.
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Calculations for preparation of isotonic solution:
multiply the quantity of each drug in the prescription by it's sodium chloride equivalent E , and subtract this value from the concentration of sodium chloride which is isotonic with body fluids (0.9 gm per 100 ml).
Explanation:
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