Question

first cell and mast cell in the range are separated by
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Answer 1

Answer:

These are very distinct types of cells involved in immunity. You could consider them different types of players in a immunological football team.

Mast cells are derived from bone marrow stem cells which have chosen to develop into myeloid granulocytes (white cells containing distinctive granules. This group includes cells which ultimately will become neutrophils, eosinophils, basophils and mast cells. The granules vary considerably between these different cell types and contain many types of proteins and enzymes with important inflammatory, antimicrobial and cell signalling actions. Granulocytes are a very important part of the immune system but unlike plasma cells do not produce antibodies. Most granulocytes circulate in the blood but mast cells are found predominantly anchored in connective tissue especially in the skin, close to blood vessels, in the lungs and parts of the immune system. Mast cells are can be involved in allergic reactions and release of their granules can lead to a wide range of symptoms. When a cell of this lineage undergoes a cancerous change it may give rise to a wide range of diseases ranging from a mild irritating skin disorder through to an aggressive form of leukaemia.

Plasma cells are one of the types of mature cells of the B lymphocyte part of the lymphoid immune system which have reached the stage of producing antibodies. They originate from bone marrow stem cells which have developed into the lymphocytic lineage. They have been activated by exposure to a specific stimulus (antigen) which makes them mature into a factory for a specific antibody tailored to that antigen. They are found throughout the body but especially in the tissues of the immune system such as the bone marrow, lymph nodes, spleen and liver as well as in many types of inflammatory changes in other tissues. When a cell of this lineage undergoes a cancerous change it may end up as myeloma, a malignant tumour of bone marrow which leads to a wide variety of complications including bone destruction, infection and kidney failure