Question

First tRNA that will attach on P site during transition process will have anticodon on it:
A) AUG
C) UAA
B) UAG
D)UAC​

Answer 1

Answer:

UAG

Explanation:

As we know that genetic code show degeneracy and multiple codons can code for same amino acid. This can be explained by Wobble hypothesis. According to Wobble hypothesis, first two bases of an mRNA codon form strong Watson-Crick base pairs with the corresponding tRNA anticodon and confer most of the coding specificity. The first base of the anticodon that pairs with the third base of the codon determines the number of codons recognized by the tRNA. The presence of C/A as first base of the anticodon confers specific base pairing which means only one codon is recognized by that tRNA. The presence of U or G means less specific pairing and two different codons may be read. The presence of inosine (I) as the first nucleotide of an anticodon means that three different codons can be recognized. The triplet "UGC" codes for cysteine. Other triplets that code for cysteine is " UGU". "UGA and UAG" are stop codons that cause termination of translation. "UGG" codes for arginine. It can be observed that multiple codons for same amino acids have same bases in first two positions and determine the specificity.