flow chart of multiple fission
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Multiple fission also occurs among protists and is common in some parasitic species. The nucleus divides repeatedly to produce a number of daughter nuclei, which eventually become the nuclei of the progeny after repeated cellular divisions. There are several kinds of multiple fission, often correlated with phases or stages in the full life cycle of a given species. The number of offspring or filial products resulting from a multiple division (or very rapid succession of binary fissions) may vary from four to dozens or even hundreds, generally in a short period of time. Modes of such multiple fission range from budding, in which a daughter nucleus is produced and split from the parent together with some of the surrounding cytoplasm, to sporogony (production of sporozoites by repeated divisions of a zygote) and schizogony (formation of multiple merozoites, as in malarial parasites). The latter two phenomena are characteristic of many protists that are obligate parasites of more advanced eukaryotes. Some multicellular algal protists reproduce via asexual spores, structures that are themselves often produced by a series of rapid fissions.