Biology, asked by kumbhajchandrak127, 11 months ago

Fluocinolone acetonide implant (retisert) for chronic cystoid macular edema in two patients with aids and a history of cytomegalovirus retinitis

Answers

Answered by BinDaSSgirL01
0
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PURPOSE:

To report the authors' experience using fluocinolone acetonide (Retisert) to treat cystoid macular edema (CME) resulting from immune recovery uveitis (IRU) in 2 acquired immunodeficiency syndrome (AIDS) patients with a history of cytomegalovirus (CMV) retinitis.

DESIGN:

Interventional case series.

METHODS:

Medical records were reviewed of 2 patients who received Retisert implantation in 3 eyes for IRU-associated inflammation and CME. Suppression of CMV disease was achieved with oral medication in one patient and with simultaneous implantation of a ganciclovir implant in the other patient.

RESULTS:

After Retisert implantation in 3 eyes in AIDS patients on HAART, improvement in CME was seen in 2 eyes. No CMV reactivation was detected during the several-month follow-up period.

CONCLUSIONS:

Retisert may be an effective treatment for CME in AIDS patients with IRU reactivation and a history of CMV retinitis.

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