For regulation of cell cycle major check point is transition
of
G1-S
G2 M
S ---> G1
M - G2...
which is major
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Explanation:
There are many checkpoints in the cell cycle, but the three major ones are: the G1 checkpoint, also known as the Start or restriction checkpoint or Major Checkpoint; the G2/M checkpoint; and the metaphase-to-anaphase transition, also known as the spindle checkpoint.
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