Formula for how many clones will be having to represent genomeof whole organism
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Explanation:
Clarke and Carbon (1976) devised a formula which calculates the probability (P) of any DNA sequence being included in a library of random fragments. In other words, 3 times (4.2/1.2) the theoretical minimum number of clones have to be used to achieve 95% probability of including a given sequence in the library.
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Answer:
The formula n = ln(1-phi f)/ln(1-f)
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