formula of frankland reagent
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They are less reactive than many other analogous organometallic reagents, such as Grignard and organolithium reagents. In 1848 Edward Frankland prepared the first organozinc compound, diethylzinc, by heating ethyl iodide in the presence of zinc metal.
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Formula of frankland reagent
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- The preparation of dialkyl zinc from zinc and alkyl iodide is called the Frankland reaction.
- Alkyl zinc has found many applications in organic synthesis because the addition of alkyl zinc to aldehydes in the presence of a chiral catalyst affords secondary alcohols with a high level of enantioselectivity.
- A complementary, and more popular approach to generate activated zinc metal is to remove zinc oxide from the metal surface by chemical reaction or entrainment, typically achieved using chemical additives such as TMSCl, 1,2‐dibromoethane, bromine, or iodine.
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