g1 to s transition is carried out by
1. MPF +cdc2 kinase
2. G1 cyclin + cdc2 kinase
3. G1 cyclin only
4. cdc2 kinase only
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Between G1 and S phase, three DNA damage checkpoints occur to ensure proper growth and synthesis of DNA prior to cell division. Damaged DNA during G1, before entry into S phase, and during S phase result in the expression of ATM/R protein.
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