Question

Gabriel phthalimide synthesis can be used to prepare

Answer 1

Primary amine is synthesize by Gabriel phthalimide rxn

Answer 2

Answer:

✔Aromatic amines cannot be prepared by Gabriel Phthalimide synthesis reaction because aryl halides do not undergo nucleophilic substitution with the anion formed by phthalimide.

✔It is used for the preparation of primary aliphatic amines.

✔Phthalimide on treatment with ethanolic potassium hydroxide forms potassium salt of phthalimide which on heating with alkyl halide followed by alkaline hydrolysis produces the corresponding primary amine.