Question

Give a detailed account of Beta oxidation of Palmitic acid​

Answer 1

Answer:

Oxidation of of palmitic acid yields 7 NADH + 7 FADH2 + 8 acetyl-CoA in 7 cycles of mitochondrial beta oxidation. ... However you have to used 2 ATP molecules for the initial activation of every fatty acid that is going to be oxidized in the mitochondria.

Answer 2

Explanation:

Energetics of β-Oxidation

Palmitoyl-CoA yields 8 acetyl-CoA molecules and 14 pairs of hydrogen atoms, by seven cycles through the β-oxidation system. Acetyl-CoA can be oxidized in the TCA cycle, used for the synthesis of fatty acid or cholesterol, or used for the formation of ketone bodies in liver. β-Oxidation of an acyl-CoA with an uneven number of carbon atoms also yields a propionyl-CoA during the acetyl-CoA acyltransferase reaction of the last cycle.

Two high-energy bonds are consumed in the activation of a fatty acid molecule. Every mole of fatty acyl-CoA that cycles through reactions 1–4 produces 1 mol of FADH2, 1 mol of NADH, and 1 mol of acetyl-CoA. On the last pass of an even-chain-length fatty acid, 2 mol of acetyl-CoA are formed; and the final pass of an odd-chain-length molecule releases 1 mol of propionyl-CoA.

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