Give an account of causes of necrosis.
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Avascular necrosis occurs when blood flow to a bone is interrupted or reduced. Reduced blood supply can be caused by:
Joint or bone trauma-An injury, such as a dislocated joint, might damage nearby blood vessels. Cancer treatments involving radiation also can weaken bone and harm blood vessels.
Fatty deposits in blood vessels-The fat (lipids) can block small blood vessels, reducing the blood flow that feeds bones.
Certain diseases-Medical conditions, such as sickle cell anemia and Gaucher's disease, also can cause diminished blood flow to bone.
so these three causes are important
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