Question

"Give an account of the chromosomal disorder in humans" (7*7 mark)​

Answer 1

Answer:

Known disorders in humans include Wolf-Hirschhorn syndrome, which is caused by partial deletion of the short arm of chromosome 4; and Jacobsen syndrome, also called the terminal 11q deletion disorder. Duplications: A portion of the chromosome is duplicated, resulting in extra genetic material.

Answer 2

Answer:

Chromosomal disorder affects the humans body such as malformations or malfunctions with the change in chromosomes.

There are three types of chromosomal disorder in humans.

• Down's syndrome
• Klinefelter's syndrome
• Turner's syndrome

Explanation:

• Down's syndrome has been caused by extra number of chromosome 21. In this disease the offspring gets 47 chromosomes. if the same kind of chromosomes are present in same kind this is known as trisomy.
• In Klinefelter's syndrome there are 47 number of chromosomes are present in the offspring $(2n+1)$.
• In Turner's syndrome there are 45 number of chromosomes are present in offspring $(2n-1)$.