Give an example of adol condensation
Answers
The Aldol addition reaction involves the addition of α-carbon of an enolizable aldehyde or ketone to the carbonyl group of another aldehyde or ketone and thus by giving a β-hydroxy carbonylcompound also known as an aldol (indicating both aldehyde and alcohol groups). The reaction is catalyzed more commonly by a base or some times by an acid.
If the β-hydroxy carbonyl compound containing an α-hydrogen undergoes subsequent dehydration to yield an α,β-unsaturated carbonyl compound, the entire process is also called as Aldol condensation. The dehydration step is possible under the aldol reaction conditions or mostly carried out by heating in presence of an acid or sometimes during acidic workup.
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the Robinson annulation reaction sequence features an aldol condensation