Give an example of racemic mixture?
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racemic mixture is a 50:50 mix of two enantiomers. No matter how many molecules are in a mixture, it is racemic if there are equal numbers of the two enantiomers. In the pharmaceutical industry, and sometimes the organic chemistry laboratory, you may hear the term enantiomeric excess. This means you have more of one enantiomer than the other. Since it's not a 50:50 mixture, a sample or a reaction that has enantiomeric excess cannot be a racemic mixture.
One way to know that you have a racemic mixture is by measuring its optical activity in a polarimeter. Because two enantiomers have equal and opposite specific rotations, a racemic mixture has a specific rotation of zero. A compound or a mixture whose specific rotation is zero is optically inactive. The bottom line: a racemic mixture will always be optically inactive
some drug molecules are chiral, and the enantiomers have different effects on biological entities. They can be sold as one enantiomer or as a racemic mixture. Examples include thalidomide, ibuprofen, and salbutamol.
One way to know that you have a racemic mixture is by measuring its optical activity in a polarimeter. Because two enantiomers have equal and opposite specific rotations, a racemic mixture has a specific rotation of zero. A compound or a mixture whose specific rotation is zero is optically inactive. The bottom line: a racemic mixture will always be optically inactive
some drug molecules are chiral, and the enantiomers have different effects on biological entities. They can be sold as one enantiomer or as a racemic mixture. Examples include thalidomide, ibuprofen, and salbutamol.
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