give reason for vitamin C play an important role of wound healing
Answers
Vitamin C has many physiologic functions in the human body. It is often aligned with wound healing because of its role in collagen formation. Vitamin C is a co-factor in proline and lysine hydroxylation, a necessary step in the formation of collagen. Hydroxyproline and hydroxylysine are essential for stabilizing the triple helix structure of collagen with strong hydrogen bonds and crosslinks. Without this stabilization, the structure disintegrates rapidly. Vitamin C also provides tensile strength to newly built collagen; otherwise, new tissue could not stretch without tearing. Tensile strength is important in pressure ulcer healing because healed pressure ulcers are susceptible to future skin breakdown. Vitamin C also is required for proper immune system function, a consideration in patients with open wounds.
Other chief functions of vitamin C include:
• antioxidant to inhibit damage to body cells
• anti-inflammatory
• necessary for the synthesis of carnitine, a molecule essential for the transport of fat to mitochondria
• plays a role in the synthesis of the neurotransmitter norepinephrine
• protects iron in the intestines from oxidation and promotes absorption
• protects vitamin E in the blood from oxidation and may recycle it to its active form.
It is often aligned with wound healing because of its role in collagen formation.Vitamin C is a co-factor in proline and lysine hydroxylation, a necessary step in collagen formation...vitamin C is also required for proper immune system function, consideration in patients with open wounds.
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