give reason why circulatory system cannot tolerate leak within it
Answers
The cardiovascular or circulatory system is designed to ensure the survival of all cells of the body at every moment and it does this by maintaining the immediate chemical environment of each cell in the body (i.e., the interstitial fluid) at a composition appropriate for that cell's normal function. The term “homeostasis” is used to denote the approximate constancy of the internal environment.
First consider the simple hypothetical case of a single spherical cell suspended in a large well-stirred volume of aqueous medium in equilibrium with room air and containing other nutrients. Oxygen availability is often a limiting factor for cell survival, and it is generally supplied to a cell by passive diffusion. As oxygen molecules diffuse into the cell, they are consumed, so that there is a progressive fall in oxygen concentration from the surface of the cell to the lowest concentration which occurs at the center of the cell. For a spherical cell with a typicaldiffusion coefficient for oxygen and an oxygen consumption of resting skeletal muscle, the critical size (radius) which is just adequately supplied with oxygen from the surrounding medium is about 1 mm. Thus, we find that diffusion puts an upper limit on the size of cells in regard to their need for oxygen.
Although diffusion is an efficient transport process over short distances as seen by the average time required for a molecule to diffuse a distance x, how can a much larger multicellular organism, such as the human body containing about 100 × 1012 cells, be adequately supplied with oxygen? For mammals, the bathing medium for cells is water and total body water is about 60% of body weight. For a 70-kg person, total body water is distributed among three compartments with the following approximate volumes: intracellular ≈23 l (33% of body weight); interstitial ≈16 l (22.5% of body weight); and circulating plasma ≈3 l (4.5% of body weight). Cells are bathed in interstitial fluid (ISF), but interstitial fluid volume is only a little more than half the intracellular fluid volume. Thus, ISF cannot be considered a large reservoir of fluid, and its composition is directly influenced by cellular metabolism.
Circulatory system cannot tolerate leak as it forms a network for supplying blood to all the organs and tissues in the body. Any damaged vessel that leads to the leakage of blood results in the formation of purple spots known as petechiae.
Leakage can lead to a fall in the blood pressure,which can ultimately lead to organ failure and finally death of the organism. It is because blood carries nutients, and oxygen to the tissues and organs and also carries away waste products from them.