give result when cross between homophlic male with homophlic female
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2
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If the boy gets his mother's X chromosome with the hemophilia gene he will have hemophilia. If he inherits his mother's other X chromosome, he will have normal blood clotting. If the baby gets the X chromosome from the father it will be a girl.
Answered by
1
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Haemophilia is an X-linked recessive disorder. Since males are hemizygous for chromosome, one copy of the affected gene in males in each cell is sufficient to cause the disorder (X
h
Y or X
h
Y ). Females with two copies of the affected gene show the disorder (X
h
X
h
or X
h
X
h
). Females heterozygous for this trait will be normal but serve as a carrier of the disease. Since father transmits its X chromosome to the daughters, not to son, so the haemophilic father would not affect the disease inheritance of his son. Son receives its X chromosome from mother which is carrier (X
h
X) which means half of her sons will get normal copy of X chromosome and another half will get the affected copy.
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