give the proportion of colorimetric solutions to be taken for performing suitability test for Dextrose
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Answer:
5% Dextrose Injection, USP solution is sterile and nonpyrogenic. It is a parenteral solution containing dextrose in water for injection intended for intravenous administration.
Each 100 mL of 5% Dextrose Injection, USP, contains dextrose monohydrate, 5 g in water for injection. The caloric value is 170 kcal/L. The osmolarity is 252 mOsmol/L (calc.), which is slightly hypotonic.
The solution pH is 4.3 (3.2 to 6.5).
This solution contains no bacteriostat, antimicrobial agent or added buffer and is intended only as a single-dose injection. When smaller doses are required the unused portion should be discarded.
5% Dextrose Injection, USP is a parenteral fluid and nutrient replenisher.
Dextrose, USP is chemically designated D-glucose monohydrate (C 6H 12O 6 • H 2O), a hexose sugar freely soluble in water. It has the following structural formula:
Water for Injection, USP is chemically designated H 2O.
The flexible container is fabricated from a specially formulated non-plasticized film containing polypropylene and thermoplastic elastomers ( freeflex® bag). The amount of water that can permeate from the container into the overwrap is insufficient to affect the solution significantly. Solutions in contact with the flexible container can leach out certain of the container’s chemical components in very small amounts within the expiration period. The suitability of the container material has been confirmed by tests in animals according to USP biological tests for plastic containers.