Question

Give the reaction of Hoffmann degradation ?​

Answer 1

Answer:

CH3CONH2+BR2+4NAOH-CH3NH2+2NABR+NA2CO3+2H2O

Answer 2

Answer :-

In Hoffmann bromamide degradation reaction, an amide reacts with bromine and aqueous solution of sodium hydroxide which produces primary amine. This a degradation reaction as primary amine in the product has one carbon lesser than primary amide (in the reactant).

Secondary and tertiary amides don’t show Hoffmann bromamide reaction. Only one unit or molecule of bromine is used in the reaction.

Primary amides show this reaction.

For reaction mechanism, refer the attachment.

Remarks :-

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