Question

Glomerular filtrate is first collected by: ​

Answer 1

Answer:

Bowman's capsule

location- nephron of kidney

Answer 2

Glomerular filtrate:

• Bowman's capsule is a cup-like sac at the beginning of the tubular components of a nephron in the mammalian kidney that performs the first step in the filtration of blood to form urine.

• A glomerulus is enclosed in the sac. Fluids from blood in the glomerulus are collected in the Bowman's capsule.

• The vascular pole is the side with afferent and efferent arteriole. The urinary pole is the side with the proximal convoluted tubule.

• Parietal layer- A single layer of simple squamous epithelium. Does not function in filtration. Visceral layer: lies just above the thickened glomerular basement membrane and is made of podocytes.

• The filtration barrier is composed of the fenestrated endothelium of the glomerular capillaries, the fused basal lamina of the endothelial cells and podocytes.

• The barrier permits the passage of water, ions and small molecules from the bloodstream into the Bowman's space.

Functions of glomerulus filtration:

• The process of filtration of the blood in the Bowman's capsule is ultrafiltration, and the normal rate of filtration is 125ml/min, equivalent to  80 times the daily blood volume.

• It is a major site for blood filtration.

• As the result , the filtrate leaving the blood plasma composed of blood plasma minus plasma protein.