Graft rejection is mediated by
(A) B-cells
(B) T-cells
(C) Plasma cells
(D) NK cells
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T-cells
The immune response to a transplanted organ consists of both cellular (lymphocyte mediated) and humoral (antibody mediated) mechanisms. Although other cell types are also involved, the T cells are central in the rejection of grafts. The rejection reaction consists of the sensitization stage and the effector stage.
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