he patient N., female, 55 years old, turned to a general practitioner about an increased level of total
cholesterol. She knew about the increase of total cholesterol from about 8 years before this day.
She didn’t take any lipid-lowering drugs, just followed hypolipidemic diet. Her father died of myocardial
infarction at the age of 40.
Laboratory analysis: Total cholesterol - 12.3 mmol / l, LDL - 8.7 mmol / L, high density lipoproteins
(HDL) - 1.1 mmol / L, triglycerides - 1.7 mmol / L, other indicators within normal limits.
On examination, the xanthelasma of the eyelids and lipoid arc of the cornea are notable. Xanthoma of the
tendons are absent.
1. Assume the most likely diagnosis for this patient.
2. Determine the phenotype of dyslipidemia according to Fredrickson classification
3. What additional laboratory and instrumental diagnostic methods should be performed to
determine the state of cardio-vascular system of this patient?
4. What are the main principles of management / treatment of this patient, considering her
anamnesis? What drugs may be used?
5. Assume a prognosis of this patient.
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