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Biochemistry actually provides the most reliable evidence of common ancestry. The points of evidence are given here.
• Metabolism - Anabolic reactions such as protein synthesis, photosynthesis and respiratory reaction are all living organisms. Also the energy released by oxidation is stored as ATP (adenosine triphosphate). It's a strong one.
• Enzymes- Most enzymes that induce biochemical reactions in organisms are similar to humans and plants with bacteria. E.g. - The enzyme involved in glycolysis and crab cycle is almost identical in both plants and animals, tropicins and amylase enzymes are similar in all animals.
• Hormones - Most of the vertebrae are some of the hormones very similar in chemistry and work. E.g. - Beef thyroid can be used for human treatment and human thyroid can be used for variation in frog tadpoles!
• Chromosomes and nucleic acids - There is a great similarity between all organisms, that they all store their genetic information in the form of DNA (except those RNA viruses) but this is a lot! Eukaryotes store DNA as linear chromosomes, while prokaryotes in the rings.
• Cytochrome C- A respiratory protein found in all eukaryotic cells, which is part of the electron transport system. It receives H+ ion in every eukaryotic cells. Humans and Chimpanzees consist of an exact related Cytochrome C.
• Hemoglobin- 2 alpha chains (each with 141 amino acids) and 2 beta chains (each containing 146 amino acids) in the protein. But there is only one amino acid difference between the gorilla and man's hemoglobin series, between the horse and man 26 amino acid difference and 10 amino acids difference between man and pig!