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Answer 1

Originally Answered: What's the difference between chromatin and chromosome?

DNA exists in Chromatin form in the nucleus. The chromatin condenses to form Chromosomes during cell division.




Inside the nucleus
The chromatin in the nucleus forms a 'beads-on-string' structure or Nucleosome. The 'beads' are octamer histone proteins and the 'string' is the double-stranded DNA. About 147 base pairs wrap around the 8-part histone protein to form a nucleosome. The nucleosomes condense to form a chromatin fiber.





Chromatin fiber organises into Chromosomesupon cell division. The chromatin is elaborately arranged and paired in mitosis. Sister chromatids are formed in case of meiosis along with pairing. After division, the DNA returns to it's looser chromatin form.

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OTHER ANSWERS



Chris Riley, Middle School Science Teacher

Answered Sep 21, 2015 · Author has 59 answers and 76.2k answer views

This is from a middle school science level:

Chromosomes are the things in the nucleus of a cell that carry genetic information. We're used to seeing them looking kind of like the letter X. You have two of each, one from Mom, the other from Dad.

Chromosomes are made of 2 chromatids. This is because you can only see them during the stage of the cell cycle called Mitosis, when the nucleus splits. At this stage, you need 2 copies of the genetic information, one to go into each new cell. So the cell has already copied the genetic information. The chromatids are joined together to form the X by a structure called a centromere.

The chromatids are made of a substance called chromatin. This is a single, very long strand of DNA. It is spiraled up a bunch of times to be small.

So, chromatin is a long strand of DNA, containing a bunch of genes. You have 23 pairs of these, 23 from each parent, for a total of 46. The chromatin is copied, so you now have 92 strands, that are each spiraled up to form the chromatids. The 2 copies of each chromatid are joined together by a centromere to form a chromosome. You have 23 pairs of these, for 46 total.

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Aashish Sharma, M.Tech. Biotechnology and Bioinformatics & English Grammar, University of Rajasthan (2014)

Answered Apr 4, 2018 · Author has 646 answers and 197.8k answer views

Chromatin- The readily stainable substance of a cell nucleus, consisting of DNA, RNA, and various proteins, that forms chromosomes during cell division.

Chromatid- A chromatid is one-half of two identical copies of a replicated chromosome During cell division , the identical copies are joined together at the region of the chromosome called the Centeomere. Joined chromatids are known as sister chromatids. Once the joined sister chromatids separate from one another in anaphase of mitosis, each is known as a daughter chromosome.

Chromosome- a chromosome is a coiled thread-like structure that contains the genetic material of organisms. A chromosome is the condensed form of a chromatin, which in turn is made up of the DNA and proteins called Histones.

So, Chromosome is said to be composed of the identical sister chromatids.