Biology, asked by akkuvava2983, 1 year ago

hemorrhagic disease due to alpha-1-antitrypsin

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Answered by SIRAJ111
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Answered by athiraajikumarcpd200
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Answer:

Explanation:

Hemorrhagic disease due to alpha-1-antitrypsin Pittsburg mutation is a rare, genetic, constitutional coagulation factor defect disorder characterized by a bleeding tendancy of variable severity due to methionine 358 to arginine replacement (Pittsburgh mutation) in the alpha-1-antitrypsin protein. Patients present with spontaneous hematomas, hematomas following minor trauma or surgery and, in female patients, ovarian hematomas after ovulation.

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