Question

Heterocyclic ring present in amino acid histidine is

Answer 1

Answer:

l -Histidine (2) is the only amino acid that contains an imidazole ring (glyoxaline) (1), an aromatic heterocyclic group with one nitrogen atom hybridized as in pyridine and the other one hybridized as in pyrrole

Answer 2

The heterocyclic ring present in amino acid histidine is the imidazole ring.

Histidine:

• Histidine is an essential -amino acid that is required for protein biosynthesis.
• It is a positively charged amino acid at physiological pH because it has an α-amino group, a carboxylic acid group, and an imidazole side chain.
• Histidine is required for protein synthesis.
• It is a member of the catalytic triad in enzymes such as serine proteases (e.g., trypsin) and plays important role in the active site.
• Histidine ammonia-lyase (histidase) in the liver and skin can convert excess histidine to trans-urocanate.
• Histidine, in high doses, may impair cognitive function and sleep.
• Because histidine is an essential amino acid, a lack of it can have a number of negative consequences.
• The most common symptoms are dry or scaly skin lesions, anemia, poor hearing, and general feelings of ill health.

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