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What is the differentiation between lyases and ligases???(write any three points)
Answers
Answer: Lyases are also called synthases. Ligases are involved in catalyzing some biochemical reactions that result in bond forming. ... The main difference between lyases and ligases is that lyases break chemical bonds in order to form new compounds whereas ligases form chemical bonds in order to combine different compounds.
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In biochemistry, a ligase is an enzyme that can catalyze the joining of two large molecules by forming a new chemical bond, usually with accompanying hydrolysis of a small pendant chemical group on one of the larger molecules or the enzyme catalyzing the linking together of two compounds, e.g., enzymes that catalyze joining of C-O, C-S, C-N, etc. In general, a ligase catalyzes the following reaction:
Ab + C → A–C + b
or sometimes
Ab + cD → A–D + b + c + d + e + f
where the lowercase letters can signify the small, dependent groups. Ligase can join two complementary fragments of nucleic acid and repair single stranded breaks that arise in double stranded DNA during replication.
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