hi friends,
How did you develop from a single cell into a person?
How relevant is epigenetics actually?
What is the mutation rate of a human cell?
Long answers
Answers
Over the course of hours, days, or months, the organism turns from a single cell called the zygote (the product of sperm meeting egg) into a huge, organized collection of cells, tissues, and organs. As an embryo develops, its cells divide, grow, and migrate in specific patterns to make a more and more elaborate body.
The epigenetics field is anticipated to contribute to understanding of the complexities of genetic regulation, cellular differentiation, embryology, aging and disease but also to allow one to systematically explore novel therapeutic avenues, ultimately leading to personalised medicine.
The average mutation rate was estimated to be approximately 2.5 x 10(-8) mutations per nucleotide site or 175 mutations per diploid genome per generation. Rates of mutation for both transitions and transversions at CpG dinucleotides are one order of magnitude higher than mutation rates at other sites.
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