Hi
How we can extract amine from mixture contain amine and aldehyde ?
Answers
Explanation:
As you must be knowing that Imine bond is prone to hydrolysis. The rate of hydrolysis gets speeded up in presence of acid or base. The stationary phase used in column like silica or alumina have acidic sites which prompt the acid hydrolysis of the imine leading to the loss of product imine (in general case) so column chromatography is not sometimes a good choice in case of schiff bases or imines.
This may or may not be true in your case as i donot know the exact nature of your compounds. I can recommend purification through solvent washing's. That is say for a hypothetical case we have an un -reacted aldehyde and unreacted amine along with the product imine. Choose a dried solvent in which the product imine is most soluble than the reactant aldehyde and ammine do multiple washings with solvent/ solvent system( work out such system over TLC for your case) and remove the solvent to get the pure imine product.
in another case use multiple solvents first the one in which aldeyde or amine is soluble to remove one of the reactants selectively then use another dried solvent to remove the second reactant selectively.
You may have to optimize the work up protocol for your system
Selective Distillation separation can also be used if the boiling points of the components of mixture are different.
If the product imine is totally insoluble in some solvent, then best method would be purification by product crystallization.
Hope it helps if it does then do mark as brainliest!!!