Histone deactylase (HDAC) catalyses the removal of acytyl group from N-terminal of histones . Which amino acid of histone is involved in this process?
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1
Answer:
Iysine
Explanation:
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The deacetylase activity has preference toward the ε-amino acetyl groups of lysine residues compared to the α-amino acetyl groups of amino-terminal amino acids in histones. Treatment of deacetylation reactions with proteinases destroyed most of the enzymatic deacetylation activity.
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1
Answer:
acetyl lysine amino acid
Explanation:
are a class of enzymes that remove acetyl groups (O=C-CH3) from an ε-N-acetyl lysine amino acid on a histone, allowing the histones to wrap the DNA more tightly. This is important because DNA is wrapped around histones, and DNA expression is regulated by acetylation and de-acetylation.
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