World Languages, asked by Anonymous, 5 months ago

hlo all pls tell what is amayloid

Answers

Answered by natrajnagappadi
1

Answer:

Amyloidosis (am-uh-loi-DO-sis) is a rare disease that occurs when an abnormal protein, called amyloid, builds up in your organs and interferes with their normal function.

Amyloid isn't normally found in the body, but it can be formed from several different types of protein. Organs that may be affected include the heart, kidneys, liver, spleen, nervous system and digestive tract.

Explanation:

Symptoms

Purpura around the eyes, a sign of amyloidosis

Purpura around the eyes Open pop-up dialog boxEnlarged tongue, a sign of amyloidosis

Enlarged tongue Open pop-up dialog box

You may not experience signs and symptoms of amyloidosis until the condition is advanced. When signs and symptoms are evident, they depend on which of your organs are affected.

Signs and symptoms of amyloidosis may include:

Swelling of your ankles and legs

Severe fatigue and weakness

Shortness of breath with minimal exertion

Unable to lie flat in bed due to shortness of breath

Numbness, tingling or pain in your hands or feet, especially pain in your wrist (carpal tunnel syndrome)

Diarrhea, possibly with blood, or constipation

Unintentional weight loss of more than 10 pounds (4.5 kilograms)

An enlarged tongue, which sometimes looks rippled around its edge

Skin changes, such as thickening or easy bruising, and purplish patches around the eyes

An irregular heartbeat

Difficulty swallowing

See your doctor if you persistently experience any of the signs or symptoms associated with amyloidosis.

Causes

There are many different types of amyloidosis. Some varieties are hereditary. Others are caused by outside factors, such as inflammatory diseases or long-term dialysis. Many types affect multiple organs, while others affect only one part of the body.

Subtypes of amyloidosis include:

AL amyloidosis (immunoglobulin light chain amyloidosis). The most common type of amyloidosis in developed countries, AL amyloidosis is also called primary amyloidosis. It usually affects the heart, kidneys, liver and nerves.

AA amyloidosis. Also known as secondary amyloidosis, this variety is usually triggered by an inflammatory disease, such as rheumatoid arthritis. Improved treatments for severe inflammatory conditions have resulted in a sharp decline in the number of cases of AA amyloidosis in developed countries. It most commonly affects the kidneys, liver and spleen.

Hereditary amyloidosis (familial amyloidosis). This inherited disorder often affects the nerves, heart and kidneys. It most commonly happens when a protein made by your liver is abnormal. This protein is called transthyretin (TTR).

Wild-type amyloidosis. This variety of amyloidosis occurs when the TTR protein made by the liver is normal but produces amyloid for unknown reasons. Formerly known as senile systemic amyloidosis, wild-type amyloidosis tends to affect men over age 70 and typically targets the heart. It can also cause carpal tunnel syndrome.

Localized amyloidosis. This type of amyloidosis often has a better prognosis than the varieties that affect multiple organ systems. Typical sites for localized amyloidosis include the bladder, skin, throat or lungs. Correct diagnosis is important so that treatments that affect the entire body can be avoided.

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