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state the chemical composition of the solid matrix of cartilage
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Articular cartilage. The articular cartilage function is dependent on the molecular composition of the extracellular matrix (ECM). The ECM consists mainly of proteogly an and collagens. ... The collagen, mostly collagen type, constrains the proteogly...
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but it's not clear to me
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Chondroitin salts.
The cartilage matrix comprises a network of collagen fibrils enmeshed in a concentrated PG solution. The collagen and PGs interact to form a porous composite fiber-reinforced organic solid matrix that is swollen with water (Mow and Hung, 2001). Collagen is 15% to 22% of the wet weight, with 4% to 7% PG, and the remainder composed of water, inorganic salts, other proteins, glycoproteins, and lipids. The matrix is divided into theoretical compartments relative to the cells (chondrocytes): pericellular, territorial, and interterritorial. There are also four successive zones beginning at the articular surface that differ in terms of matrix composition, water concentration, collagen fibril orientation, and cellular alignment and morphology. These are termed superficial, intermediate (transitional or middle), deep (radial) and calcified cartilage zones.
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Adira.
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Regards,
Adira.
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