how Amp and GMP are biologically sybthesized.
Answers
Answered by
1
Answer:
Please mark me Brainlist
Explanation:
GMP is synthesized either from IMP through the de novo purine pathway or from guanine through the salvage purine pathways, and it is the precursor molecule of GDP, GTP, ppGpp and cGMP, whose biological importance is well known [3,4].
Inosinate is the branch point in the synthesis of AMP and GMP. The reactions leading away from inosinate are sites of feedback inhibition.
IMP is the major branch-point in the formation of all purine nucleotides. In one branch, IMP is irreversibly converted into AMP in two enzymatic steps. First, succinyl-AMP (sAMP) is formed by condensation of aspartic acid and IMP catalyzed by adenylosuccinate synthase. This reaction is driven by GTP hydrolysis.
Similar questions