how are tight junctions formed between neighbouring cells of epithelial tissue
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→ The strands are formed by transmembrane proteins on the surfaces of the cell membranes that are adjacent to each other. Claudins are important in forming tight junctions, while occludins play more of a role in keeping the tight junction stable and maintaining the barrier between cells that keeps unwanted molecules out.
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Tight junctions seal adjacent epithelial cells in a narrow band just beneath their apical surface. They consist of a network of claudins and other proteins. Tight junctions perform two vital functions: They limit the passage of molecules and ions through the space between cells.
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