Question

how are you man being responsible for the depletion of vegetation and wildlife

Answer 1

humans build homes and structures, and we eat. But we do these things like no other life does on the planet.

when we cut down trees for timber and wood and fuel, or clear forests to set up farm lands, houses, industries, etc, we greatly deplete the vegetation of the world- this now has a chain reaction on wildlife, because plant eating animals and insects depend on vegetation to survive. And when there are no herbivores around, carnivores go hungry and eventually die out.. On a large scale extinction possibly follows for some species.