How calcium helps in formation of mitotuc spindle
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Calcium-containing solutions were microinjected into dividing PtK1 cells to assess the effect of calcium ion concentration on the morphology and physiology of the mitotic spindle. ... An increase in the concentration of free calcium ions during metaphase appears to stimulate the onset of anaphase.
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Concentration of Ca2+ in cells is critical for the cell cycle progression. During mitosis, intracellular Ca2+ increases and induces chromosome condensation, spindle fibre formation and chromosome segregation, which are processes required for successful cell division2,3,4.
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