How do cell stop dividing?
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Summary. Aging mammalian cells can stop dividing and enter senescence if they are damaged or have defective telomeres. Senescence protects against tumor formation, and tumor suppressor genes include some that regulate cell division and lead to senescence.
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Cell division is a normal process. Mechanisms exist to ensure DNA replication occurs correctly and the environmental conditions are favorable for cell division. Replication errors may also be corrected after they occur. Normal cells stop dividing when there is genetic damage or conditions are not favorable.
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