Question

How do drugs target specific signal transduction pathways and alter cellular response?

Answer 1

Signal transduction pathways regulate many important cellular functions such as growth, differentiation, metabolism, and survival. ... As aresult, the RTKs and their growth factors have become a rational targetfor therapeutic interventions usingspecific antibodies and small-molecule inhibitory drugs.

Answer 2

ANSWER

Drugs usually target one particular molecular target (i.e., protein) in a particular signaling cascade. Most drugs inhibit these proteins, although a very few select drugs activate them.

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