How do penicillin acts on diease causing organism?
Answers
How does penicillin act on disease-causing organisms?
Penicillin, an antibiotic acts on prokaryotic cells by inhibiting their cell wall synthesis. They directly inhibit the transpeptidation reaction and does not allow the formation of penta-glycine residual chain between L-lysine and D-alanine subunits of the amino acid chains linked to the N-acetyl muramic acid.
The naturally obtained Penicillin drugs like Penicillin G or V are narrow spectrum drugs and can inhibit only the growth of gram positive organisms, whereas the semi synthetically produced penicillin like ampicillin is a broad spectrum drug and acts on both gram positive and gram negative.
Another interesting mode of action of this drug is that it activates the holin proteins of the cell and causes the cell to lyse itself.
Penicillin is the first ever medicine which was discovered .Penicillin is an antibiotic which helps to prevent bad bacteria on any surface.In short penicillin is an antibiotic.