How does administration of alpha interferons helps in cancer patiens?
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Alpha-interferon is usually given in a two-step process. During the first step (induction), the drug is given in a vein (intravenously). In the second step, the drug is given by injections under the skin, usually in the abdomen or thigh. Alpha-interferon is used to treat kidney (renal) tumors, melanoma, multiple myeloma, carcinoid tumors and some types of lymphoma and leukemia.Alpha-interferon is also used to treat hepatitis infections (Rebetron®, Rebetol®). A new version of alpha-interferon (Sylatron®) was approved in 2011 for the treatment of melanoma. This new form allows the drug to last for a longer period of time in the body.
Mechanism:
Alpha-interferon is a naturally occurring proteinthat is found in the body in small amounts. Use of Alpha-interferon treatments lead to inhibition of tumor cell protein production, which also helps by prolonging the cell cycle and modulating oncogene expression. Despite this, the exact mechanism of anti tumor action remains unknown.
Mechanism:
Alpha-interferon is a naturally occurring proteinthat is found in the body in small amounts. Use of Alpha-interferon treatments lead to inhibition of tumor cell protein production, which also helps by prolonging the cell cycle and modulating oncogene expression. Despite this, the exact mechanism of anti tumor action remains unknown.
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Alpha inteterferon interferons can help cells to defend the mselues against viral infection and are used in the treatment. of some cancer to boost the body' s ability to eliminate cancer cells.
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