How does carbon mono oxide acts as a poison
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Carbon monoxide is dangerous because it bonds much more tightly to the hemoglobin than does oxygen. Once hemoglobin combines with carbon monoxide to form carboxyhemoglobin, its ability to combine with oxygen is competely lost.
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Carbon monoxide binds with haemoglobin within affinity 200 times greater than oxygen ...
It binds at the same site at which oxygen binds ...That is with haem component of haemoglobin
It forms are very stable Complex called the carboxyhemoglobin and shifts that dissociation curve to left...
It therefore prevents the oxygen released into the tissue from hemoglobin resulting in stagnant hypoxia .....
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