Question

how does chemical nature of the soil change due to continued use of chemical fertilizers

Answer 1

The chemical nature of the soli changes due to continuous use of fertilisers as using fertilisers continuously can kill many useful microorganisms present in the soil which hekp in renewing the soil . Also it kills the farmers friend earthworms in the soil that are responsible for hadtening the soil.
ALSO fetilisers provide soil only nutrients and does not makes it fertile and humus.
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Answer 2

The continuous use of chemical fertilizers in a particular area or crop field leads to loss of soil fertility.