How does natural selection different from genetic drift?
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Unlike natural selection, genetic drift does not depend on an allele's beneficial or harmful effects. Instead, drift changes allele frequencies purely by chance, as random subsets of individuals (and the gametes of those individuals) are sampled to produce the next generation.
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The key distinction is that in genetic drift allele frequencies change by chance, whereas in natural selection allele frequencies change by differential reproductive success. Natural selection is the process by which the most adaptive traits for an environment become more common generation after generation.
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