how does nucleolus produce ribosomes??
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Answer:
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Explanation:
The most prominent substructure within the nucleus is the nucleolus (see Figure 8.1), which is the site of rRNA transcription and processing, and of ribosome assembly. As discussed in the preceding chapter, cells require large numbers of ribosomes to meet their needs for protein synthesis. Actively growing mammalian cells, for example, contain 5 million to 10 million ribosomes that must be synthesized each time the cell divides. The nucleolus is a ribosome production factory, designed to fulfill the need for large-scale production of rRNAs and assembly of the ribosomal subunits.
Ribosomal RNA genes. Each rRNA gene is a single transcription unit containing the 18S, 5.8S, and 28S rRNAs and transcribed spacer sequences. The rRNA genes are organized in tandem arrays, separated by nontranscribed spacer DNA.
To meet the need for transcription of large numbers of rRNA molecules, all cells contain multiple copies of the rRNA genes. The human genome, for example, contains about 200 copies of the gene.
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