Question

How does sickle cell disease exemplify the concept of pleiotropy

Answer 1

Answer:

Sickle cell anemia is a pleiotropic disease because the expression of a single mutated HBB gene produces numerous consequences throughout the body. The mutated hemoglobin forms polymers and clumps together causing the deoxygenated sickle red blood cells to assume the disfigured sickle shape.

Explanation:

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Answer 2

Explanation:

Pleiotropy means one gene can show many effects. The gene of sickle cell anaemia controls

1. cell shape

2. resistance to malaria.

Thus it controls 2 characters showing pleioptropy.

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